Wandering Adventure Party

Stanford Cures Type-1 Diabetes in Mice Without Insulin or Immune Suppressionhttps://www.goodnewsnetwork.org/stanford-cures-type-1-diabetes-in-mice-without-insulin-or-immune-suppression/#goodnews #science #health #medicine #diabetes

Cool Tesla trees.

Hello, I am crossposting this as I noticed this community also has no rules, and it’s been noticed that the top comment on a lot of posts is asking for a “No clickbait” rule and a dislike of all the spam extremely low quality articles that get posted.

This is amazing news. Man, I wish we focused on stuff like this instead of raping or murdering kids.🇺🇲

Milk based plastic was one of the first man made plastics produced back in 1890. Not 1980, 1890. https://en.wikipedia.org/wiki/Timeline_of_plastic_development

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ABSTRACT Chemodynamic therapy (CDT) is an emerging cancer treatment that employs transition metal–based nanoagents to catalyze the conversion of elevated intracellular hydrogen peroxide in malignant cells into cytotoxic hydroxyl radicals (•OH) via Fenton-like reactions. Recent developments have also introduced CDT agents that generate singlet oxygen (1O2) through the Russell mechanism. However, current nanoplatforms efficiently produce either •OH or 1O2, but not both, and often exhibit suboptimal catalytic activity, thereby limiting the sufficient production of reactive oxygen species (ROS) required for cancer eradication. This report introduces a ferrous metal–organic framework, Fe(II)-TCPP (tetrakis(4-carboxyphenyl)porphyrin), as the first nanoagent capable of simultaneously and effectively generating •OH and 1O2 through dual catalytic pathways. Its nanoneedle-like morphology increases the surface area and promotes enhanced ROS production. Cell studies demonstrated selective intracellular generation of •OH and 1O2 in cancer cells, resulting in targeted cytotoxicity while sparing non-malignant cells. Systemic administration of Fe(II)-TCPP in a breast cancer mouse model resulted in preferential tumor accumulation, robust intratumoral ROS generation, cancer eradication, and prevention of recurrence without systemic toxicity. These findings mark a foundational advance in CDT nanoagents by integrating Fenton and Russell mechanisms into a single platform, enabling the design of multifunctional catalysts with enhanced ROS output and therapeutic efficacy.

I hope they actual deliver. Dental care is still the equivalent of wooden pegs.

Sponges are among earth’s most ancient animals, but exactly when they evolved has long puzzled scientists. Genetic information from living sponges, as well as chemical signals from ancient rocks, suggest sponges evolved at least 650 million years ago. This evidence has proved highly controversial as it predates the fossil record of sponges by a minimum of 100 million years. Now an international team of scientists led by Dr Eleonora Rossi, from the University of Bristol’s School of Biological Sciences, have solved this conflict by examining the evolution of sponge skeletons. The research is published in Science Advances.

Here I thought it was going to say morning people, i.e., those who comment early in the day, are more likely to make hate comments.

This. We’re all overworked so we all have less energy for things like keeping ourselves fit. And actually exercising really doesn’t sell itself either, it hurts and it’s hot and I’m still trying to catch my damn breath from my sets earlier. Stupid maintenance. But it beats the hell out of literally slowly suffocating in my chair at my desk.

It was usually concrete, as that’s what most outdoor courts are made of in the States. That’s kinda the whole point, i.e. not wooden floors. That’s not correct about the NBA-level forces, as occasionally playing indoors instantly produced that range of squeaking sounds. Little kids produced those sounds as well. It’s just the dynamic of sneakers upon wood, essentially.

Usually when data collection happens, scientist cannot quite explain it for some time, until they can. This is really pure sensationalism, adds zero information to the article.

In this study led by Jie V. Zhao, Yitang Sun, Junmeng Zhang, and Kaixiong Ye from the University of Hong Kong and the University of Georgia, researchers investigated whether two amino acids, phenylalanine and tyrosine, affect how long people live (lifespan). The results suggest that higher levels of tyrosine are linked to shorter life expectancy in men, pointing to potential sex-specific approaches to promoting longevity.

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Here is the original article by Germany’s Saarland University: Signs on Stone Age objects: Precursor to written language dates back 40,000 years

going from a simple though experiment to being able to quantify the thermodynamics of information is one of my favorite concepts.

Launched in 1998, the event has exploded in size as birding has become increasingly popular across the globe and apps make identification and data submission more accessible. Last year, more than 830,000 people participated in the event, digitally capturing around 70 percent of the world’s avian species everywhere from Australia to Canada. This year, the event, which took place from Feb. 14 to 17, had record-breaking levels of participation. The global datasets generated during the Great Backyard Bird Count and other similar events throughout the year help scientists track how bird populations are changing across time and space, capturing what Cornell Lab’s Mya Thompson calls one of “the heartbeats of the planet.” But they also show the ways this heartbeat is faltering in the face of climate change and habitat loss. Experts are rushing to figure out how to slow bird losses before they flatline.

Not really. It needs to apply unitary operators to elements in Hilbert space, which is essentially multiplying matrices onto vectors. Which you could do by multiplying the involved numbers one by one, as most classical methods would, but then you’re missing the point of using a quantum computer.

The size of seven libraries of Congress!