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  3. Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

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  • KingK King

    Study

    The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

    The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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    tollana1234567@lemmy.today
    wrote on last edited by tollana1234567@lemmy.today
    #42

    thats why some people get a rash at the tattoo sites, or it triggers shingles. make sense since macrophages clean up melanin pigment produced by post-inflammatory hyperpigmentation, a brown spot after a severe pimple or something.

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    • Björn TantauB Björn Tantau

      I have the opposite problem, my immune system is in overdrive. I should get a tattoo to reign it in.

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      tollana1234567@lemmy.today
      wrote on last edited by
      #43

      i feel like that would cause an immediate inflammation, if your immune system is dysregulated, it would have a likely opposite effect of what it suppose to do. ive seen alot of people in tattoo sub said they had a reaction to the tattoo after its done.

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      • P03 LockeP P03 Locke

        There are far too many humans with tattoos that could have been researched extensively, but they chose mice. Mice do not have the same kind of skin density as humans, and I doubt a tattoo artist or researcher would have the talent to tattoo a mouse’s skin.

        There’s just so many things wrong with using mice in this study. So many bad ratios with the size of the animal. I mean, for fuck’s sake, tattoo artists already practice on pig skin. Pigs would have been a better analogue, but honestly, they should have picked the millions of humans who were already tattooing themselves.

        Of course, if they did that, they wouldn’t get the same result and be able to push this sensationalist science news title, now would they? Except, in this case, we’ve gone from research paper to straight to sensationalist news title in one step! Just let the institute PR department push the narrative for you, without having to wait for that pesky news cycle to crawl through the telephone game.

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        leftzero@lemmy.dbzer0.com
        wrote on last edited by leftzero@lemmy.dbzer0.com
        #44

        Just use pigs.

        Basically the same thing as a human (except for the opposable thumbs, which explains us eating them), but cleaner and smarter on average.

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        • T Thymos

          I suppose I would be in that crowd. I’m an atheist, but I think the whole tattooing thing is kinda stupid. To each their own of course, I don’t care if anyone gets a tattoo, but the culture around it annoys me and I think it’s a waste of one’s body. I do like some of the art styles, but why not just print it on a shirt and wear it?

          That being said, I think it’s petty bad if it turns out the ink causes a higher risk of disease. Like with cigarettes in the past people weren’t informed about the consequences before making their choices. That sucks and I don’t wish it on anyone.

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          leftzero@lemmy.dbzer0.com
          wrote on last edited by
          #45

          Like with cigarettes in the past people weren’t informed about the consequences before making their choices.

          Yeah, but the tobacco cartels had performed studies which clearly demonstrated how absolutely horrible their shit was and not only not made them public, but used them to maximise addiction (and cancer, as a side effect they didn’t give a single shit about).

          I very much doubt the tattoo industry has ever studied anything.

          T 1 Reply Last reply
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          • KingK King

            Study

            The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

            The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

            stravanasuP This user is from outside of this forum
            stravanasuP This user is from outside of this forum
            stravanasu
            wrote on last edited by pglpm@lemmy.ca
            #46

            Why not be a professional scientist by:

            • adding “in mice” to the title;
            • using modern statistical methods instead of continuously discredited procedures like p-values?
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            • G gusgalarnyk@lemmy.world

              Why make this comment encouraging bad behavior? This feels like injected negativity for negativity sake. Idk man, be the change you want to see in your community.

              D This user is from outside of this forum
              D This user is from outside of this forum
              derek@infosec.pub
              wrote on last edited by
              #47

              I agree with you in sentiment, however; I believe the comment you’re replying to was intended as a joke.

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              • G gusgalarnyk@lemmy.world

                Why make this comment encouraging bad behavior? This feels like injected negativity for negativity sake. Idk man, be the change you want to see in your community.

                A This user is from outside of this forum
                A This user is from outside of this forum
                auraithx@lemmy.dbzer0.com
                wrote on last edited by
                #48

                It was sarcasm nerd

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                • A answersplease77@lemmy.world

                  followed by a chronic phase that can persist for years.

                  how many years? am I doomed for life because what I did to my body when I was 18 😞

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                  auraithx@lemmy.dbzer0.com
                  wrote on last edited by auraithx@lemmy.dbzer0.com
                  #49

                  I got a tattoo on my leg when I was 17.

                  36 now and I’m the past year it’s gotten ridiculously itchy, bumpy and my skin is rejecting the ink and spitting it up in little spots.

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                  • P03 LockeP P03 Locke

                    There are far too many humans with tattoos that could have been researched extensively, but they chose mice. Mice do not have the same kind of skin density as humans, and I doubt a tattoo artist or researcher would have the talent to tattoo a mouse’s skin.

                    There’s just so many things wrong with using mice in this study. So many bad ratios with the size of the animal. I mean, for fuck’s sake, tattoo artists already practice on pig skin. Pigs would have been a better analogue, but honestly, they should have picked the millions of humans who were already tattooing themselves.

                    Of course, if they did that, they wouldn’t get the same result and be able to push this sensationalist science news title, now would they? Except, in this case, we’ve gone from research paper to straight to sensationalist news title in one step! Just let the institute PR department push the narrative for you, without having to wait for that pesky news cycle to crawl through the telephone game.

                    B This user is from outside of this forum
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                    bookmeat@lemmynsfw.com
                    wrote on last edited by
                    #50

                    You’re freaking out over over a single study. This is the beginning of a more comprehensive investigation. Chill your cornhole 🙂

                    P03 LockeP 1 Reply Last reply
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                    • P03 LockeP P03 Locke

                      And yet, we manage to have hundreds of thousands of studies written about humans with human subjects. This sounds like a boatload of excuses that could be summed up as “science is hard”. Sure, it’s hard, but it’s better than putting out a flawed study that can’t scale properly.

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                      Caveman
                      wrote on last edited by
                      #51

                      Sure, the study would be best if we did a randomised double blind study on a sample of 100 people that all are going to get a tattoo anyway but that doesn’t make the mouse study irrelevant.

                      Mice and humans, although very different in appearance have biomechanics that are very similar. For every human study you could make a 20 mouse studies with the same funding so you could do a lot more exploration.

                      This study found something, notably that ink in the blood affected the immune system. This just means that future studies are needed like injecting people with tattoo ink and blood samples diagnosis after tattoo to see how much ink is in the blood. If confirmed this will push tattoo ink manufacturers to develop a new ink that eliminates the effect and we can all enjoy safer more effective tattooing.

                      This study is not flawed, it’s pushing human knowledge forward like it always does.

                      P03 LockeP 1 Reply Last reply
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                      • L leftzero@lemmy.dbzer0.com

                        Like with cigarettes in the past people weren’t informed about the consequences before making their choices.

                        Yeah, but the tobacco cartels had performed studies which clearly demonstrated how absolutely horrible their shit was and not only not made them public, but used them to maximise addiction (and cancer, as a side effect they didn’t give a single shit about).

                        I very much doubt the tattoo industry has ever studied anything.

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                        Thymos
                        wrote on last edited by
                        #52

                        Oh definitely, the tobacco industry is way worse. Tattoo artists (at least in my county) have to follow hygiene regulations and aren’t allowed to tattoo minors, and there don’t seem to be any issues with this. There isn’t any incentive for them to cause harm to their customers, on the contrary, so I don’t blame them for this. If tattooing poses serious health risks like this study suggests, it would suck for everyone involved.

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                        • Øπ3ŕO Øπ3ŕ

                          It’s good that you’ve expressed misconception as the source of this opinion, and admitted to your lack of understanding. The rest of the work could fall in nicely, if you put the effort forth. I’ll give ya one for free: “the culture around it” isn’t some singular entity, but a varied and colorful amalgam of countless inspirations, backgrounds, beliefs, reasons, etc., and the only thing that oversimplifying does here is stunt your personal growth.

                          You got this. 🤘🏼

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                          Thymos
                          wrote on last edited by
                          #53

                          Thanks, I’m good.

                          Øπ3ŕO 1 Reply Last reply
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                          • J jacksilver@lemmy.world

                            And yet things like asbestos, lead, and smoking all took way longer than you’d expect (given they were a lot more universal).

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                            azertyfun@sh.itjust.works
                            wrote on last edited by
                            #54

                            All three of your examples were known to cause ill effects for centuries. The ancient Romans knew the asbestos mines were killing their slaves. Their overuse during the 20th century was not due to ignorance but corporate lobbying and political complacency.

                            The lobbyist play is to fund counter-studies to sow FUD even though the scientific consensus that [X Bad] is well established, because it gives an easy out for bought out politicians. However the tatoo lobby is certainly not one that I expect to be have the pull to fund FUD scientific studies to delay legislation, and if they are doing that it should be pretty easy to point to.

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                            • underpantsweevil@lemmy.worldU underpantsweevil@lemmy.world

                              It’s just tiresome to hear these hyperventilating articles without any real measure of the degree of risk or long term consequences.

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                              faythofdragons@slrpnk.net
                              wrote on last edited by
                              #55

                              Honestly, I think that shitty science reporting like this is fuel for the normie to science skeptic pipeline.

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                              • D dozensofdonner@mander.xyz

                                Ah pretty interesting. Good to clarify that its in mice, not humans.

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                                aldente@sh.itjust.works
                                wrote on last edited by
                                #56

                                Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                                • KingK King

                                  Study

                                  The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                  The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                  B This user is from outside of this forum
                                  B This user is from outside of this forum
                                  bluesheep@sh.itjust.works
                                  wrote on last edited by
                                  #57

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                                  • KingK King

                                    Study

                                    The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                    The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                                    jhex@lemmy.world
                                    wrote on last edited by jhex@lemmy.world
                                    #58

                                    how low? weakened by how much?

                                    I think they leave that out on purpose so they can make these sensational claims… if your immune system takes a 0.02% hit, nobody would care

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                                    • KingK King

                                      Study

                                      The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                      The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                      😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                                      😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                                      😈MedicPig🐷BabySaver😈
                                      wrote on last edited by
                                      #59

                                      Ha, get bent.

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                                      • P03 LockeP P03 Locke

                                        And yet, we manage to have hundreds of thousands of studies written about humans with human subjects. This sounds like a boatload of excuses that could be summed up as “science is hard”. Sure, it’s hard, but it’s better than putting out a flawed study that can’t scale properly.

                                        bonenodeB This user is from outside of this forum
                                        bonenodeB This user is from outside of this forum
                                        bonenode
                                        wrote on last edited by
                                        #60

                                        You don’t need to sum it up as science is hard but also as science is expensive. They might simply not have gotten funding for something as that.

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                                        • KingK King

                                          Study

                                          The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                          The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                                          altphoto@lemmy.today
                                          wrote on last edited by
                                          #61

                                          Link Preview Image
                                          Tattoos - Mander

                                          Lemmy

                                          favicon

                                          (mander.xyz)

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