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  3. Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

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  • G gusgalarnyk@lemmy.world

    Why make this comment encouraging bad behavior? This feels like injected negativity for negativity sake. Idk man, be the change you want to see in your community.

    A This user is from outside of this forum
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    auraithx@lemmy.dbzer0.com
    wrote on last edited by
    #48

    It was sarcasm nerd

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    • A answersplease77@lemmy.world

      followed by a chronic phase that can persist for years.

      how many years? am I doomed for life because what I did to my body when I was 18 😞

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      auraithx@lemmy.dbzer0.com
      wrote on last edited by auraithx@lemmy.dbzer0.com
      #49

      I got a tattoo on my leg when I was 17.

      36 now and I’m the past year it’s gotten ridiculously itchy, bumpy and my skin is rejecting the ink and spitting it up in little spots.

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      • P03 LockeP P03 Locke

        There are far too many humans with tattoos that could have been researched extensively, but they chose mice. Mice do not have the same kind of skin density as humans, and I doubt a tattoo artist or researcher would have the talent to tattoo a mouse’s skin.

        There’s just so many things wrong with using mice in this study. So many bad ratios with the size of the animal. I mean, for fuck’s sake, tattoo artists already practice on pig skin. Pigs would have been a better analogue, but honestly, they should have picked the millions of humans who were already tattooing themselves.

        Of course, if they did that, they wouldn’t get the same result and be able to push this sensationalist science news title, now would they? Except, in this case, we’ve gone from research paper to straight to sensationalist news title in one step! Just let the institute PR department push the narrative for you, without having to wait for that pesky news cycle to crawl through the telephone game.

        B This user is from outside of this forum
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        bookmeat@lemmynsfw.com
        wrote on last edited by
        #50

        You’re freaking out over over a single study. This is the beginning of a more comprehensive investigation. Chill your cornhole 🙂

        P03 LockeP 1 Reply Last reply
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        • P03 LockeP P03 Locke

          And yet, we manage to have hundreds of thousands of studies written about humans with human subjects. This sounds like a boatload of excuses that could be summed up as “science is hard”. Sure, it’s hard, but it’s better than putting out a flawed study that can’t scale properly.

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          Caveman
          wrote on last edited by
          #51

          Sure, the study would be best if we did a randomised double blind study on a sample of 100 people that all are going to get a tattoo anyway but that doesn’t make the mouse study irrelevant.

          Mice and humans, although very different in appearance have biomechanics that are very similar. For every human study you could make a 20 mouse studies with the same funding so you could do a lot more exploration.

          This study found something, notably that ink in the blood affected the immune system. This just means that future studies are needed like injecting people with tattoo ink and blood samples diagnosis after tattoo to see how much ink is in the blood. If confirmed this will push tattoo ink manufacturers to develop a new ink that eliminates the effect and we can all enjoy safer more effective tattooing.

          This study is not flawed, it’s pushing human knowledge forward like it always does.

          P03 LockeP 1 Reply Last reply
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          • L leftzero@lemmy.dbzer0.com

            Like with cigarettes in the past people weren’t informed about the consequences before making their choices.

            Yeah, but the tobacco cartels had performed studies which clearly demonstrated how absolutely horrible their shit was and not only not made them public, but used them to maximise addiction (and cancer, as a side effect they didn’t give a single shit about).

            I very much doubt the tattoo industry has ever studied anything.

            T This user is from outside of this forum
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            Thymos
            wrote on last edited by
            #52

            Oh definitely, the tobacco industry is way worse. Tattoo artists (at least in my county) have to follow hygiene regulations and aren’t allowed to tattoo minors, and there don’t seem to be any issues with this. There isn’t any incentive for them to cause harm to their customers, on the contrary, so I don’t blame them for this. If tattooing poses serious health risks like this study suggests, it would suck for everyone involved.

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            • Øπ3ŕO Øπ3ŕ

              It’s good that you’ve expressed misconception as the source of this opinion, and admitted to your lack of understanding. The rest of the work could fall in nicely, if you put the effort forth. I’ll give ya one for free: “the culture around it” isn’t some singular entity, but a varied and colorful amalgam of countless inspirations, backgrounds, beliefs, reasons, etc., and the only thing that oversimplifying does here is stunt your personal growth.

              You got this. 🤘🏼

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              Thymos
              wrote on last edited by
              #53

              Thanks, I’m good.

              Øπ3ŕO 1 Reply Last reply
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              • J jacksilver@lemmy.world

                And yet things like asbestos, lead, and smoking all took way longer than you’d expect (given they were a lot more universal).

                A This user is from outside of this forum
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                azertyfun@sh.itjust.works
                wrote on last edited by
                #54

                All three of your examples were known to cause ill effects for centuries. The ancient Romans knew the asbestos mines were killing their slaves. Their overuse during the 20th century was not due to ignorance but corporate lobbying and political complacency.

                The lobbyist play is to fund counter-studies to sow FUD even though the scientific consensus that [X Bad] is well established, because it gives an easy out for bought out politicians. However the tatoo lobby is certainly not one that I expect to be have the pull to fund FUD scientific studies to delay legislation, and if they are doing that it should be pretty easy to point to.

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                • underpantsweevil@lemmy.worldU underpantsweevil@lemmy.world

                  It’s just tiresome to hear these hyperventilating articles without any real measure of the degree of risk or long term consequences.

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                  faythofdragons@slrpnk.net
                  wrote on last edited by
                  #55

                  Honestly, I think that shitty science reporting like this is fuel for the normie to science skeptic pipeline.

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                  • D dozensofdonner@mander.xyz

                    Ah pretty interesting. Good to clarify that its in mice, not humans.

                    A This user is from outside of this forum
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                    aldente@sh.itjust.works
                    wrote on last edited by
                    #56

                    Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                    • KingK King

                      Study

                      The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                      The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                      B This user is from outside of this forum
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                      bluesheep@sh.itjust.works
                      wrote on last edited by
                      #57

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                      • KingK King

                        Study

                        The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                        The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                        J This user is from outside of this forum
                        jhex@lemmy.world
                        wrote on last edited by jhex@lemmy.world
                        #58

                        how low? weakened by how much?

                        I think they leave that out on purpose so they can make these sensational claims… if your immune system takes a 0.02% hit, nobody would care

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                        • KingK King

                          Study

                          The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                          The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                          😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                          😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                          😈MedicPig🐷BabySaver😈
                          wrote on last edited by
                          #59

                          Ha, get bent.

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                          • P03 LockeP P03 Locke

                            And yet, we manage to have hundreds of thousands of studies written about humans with human subjects. This sounds like a boatload of excuses that could be summed up as “science is hard”. Sure, it’s hard, but it’s better than putting out a flawed study that can’t scale properly.

                            bonenodeB This user is from outside of this forum
                            bonenodeB This user is from outside of this forum
                            bonenode
                            wrote on last edited by
                            #60

                            You don’t need to sum it up as science is hard but also as science is expensive. They might simply not have gotten funding for something as that.

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                            • KingK King

                              Study

                              The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                              The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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                              altphoto@lemmy.today
                              wrote on last edited by
                              #61

                              Link Preview Image
                              Tattoos - Mander

                              Lemmy

                              favicon

                              (mander.xyz)

                              S 1 Reply Last reply
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                              • KingK King

                                Study

                                The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                arscynic@lemmy.mlA This user is from outside of this forum
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                                arscynic@lemmy.ml
                                wrote on last edited by
                                #62

                                Steve-O is still alive; humanity will be fine.

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                                • stravanasuP stravanasu

                                  Why not be a professional scientist by:

                                  • adding “in mice” to the title;
                                  • using modern statistical methods instead of continuously discredited procedures like p-values?
                                  M This user is from outside of this forum
                                  M This user is from outside of this forum
                                  monkdervierte@lemmy.zip
                                  wrote on last edited by
                                  #63
                                  • adding “in mice” to the title;

                                  Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                  P03 LockeP 1 Reply Last reply
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                                  • J jhex@lemmy.world

                                    how low? weakened by how much?

                                    I think they leave that out on purpose so they can make these sensational claims… if your immune system takes a 0.02% hit, nobody would care

                                    P This user is from outside of this forum
                                    P This user is from outside of this forum
                                    Phoenixz
                                    wrote on last edited by
                                    #64

                                    You’d care if it’s a 20% hit, though.

                                    But you’re completely right, without any details, the claims are rather empty at best

                                    J 1 Reply Last reply
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                                    • KingK King

                                      Study

                                      The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                      The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                      gmtom@lemmy.worldG This user is from outside of this forum
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                                      gmtom@lemmy.world
                                      wrote on last edited by
                                      #65

                                      Surely someone could check this by doing a statistical analysis of cancer patients with tattoos vs how many of the general population has tattoos?

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                                      • G gusgalarnyk@lemmy.world

                                        Why make this comment encouraging bad behavior? This feels like injected negativity for negativity sake. Idk man, be the change you want to see in your community.

                                        S This user is from outside of this forum
                                        S This user is from outside of this forum
                                        sendmephotos@lemmy.world
                                        wrote on last edited by
                                        #66

                                        Because I am a sarcastic fuck.

                                        1 Reply Last reply
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                                        • KingK King

                                          Study

                                          The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                          The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                          S This user is from outside of this forum
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                                          sinadjetivos@lemmy.world
                                          wrote on last edited by
                                          #67

                                          The full paper is here and, as usual, it’s hardly anything and decontextualized in order to get a publishable result.

                                          This one is so bad that it doesn’t use established baselines or do any form of statistical analysis on the results instead opting for their own “baseline” measurements using very small sample sizes. It also plays a smoke and mirrors game where it shows a result for short term immunological response and then uses that to insinuate the ‘slightly reduced but still likely well within the error of the poor control’ long term effects are worth noting.

                                          Other major flaws:

                                          • As others have mentioned, mice are a terrible model for this as their skin is very thin and proper tattooing is near impossible.
                                          • They mention verifying with human cadavers but don’t include any data from those.
                                          • There was no control group, the baseline was an untreated mouse, not one with an acute foot trauma.
                                          • Mice age very quickly, best I can tell the immunological markers weren’t age controlled. 2 months out of a <2 year lifespan is a lot of aging. Again, if there was a proper control to measure against.
                                          • The obsfucation of the raw data into cheesy and unreadable box and whisker plots is hella suspicious.

                                          At best it’s a very poorly communicated and poorly designed experiment but I suspect that’s due to it result hunting.

                                          P03 LockeP H 2 Replies Last reply
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