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  3. Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response

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  • L leftzero@lemmy.dbzer0.com

    Like with cigarettes in the past people weren’t informed about the consequences before making their choices.

    Yeah, but the tobacco cartels had performed studies which clearly demonstrated how absolutely horrible their shit was and not only not made them public, but used them to maximise addiction (and cancer, as a side effect they didn’t give a single shit about).

    I very much doubt the tattoo industry has ever studied anything.

    T This user is from outside of this forum
    T This user is from outside of this forum
    Thymos
    wrote on last edited by
    #52

    Oh definitely, the tobacco industry is way worse. Tattoo artists (at least in my county) have to follow hygiene regulations and aren’t allowed to tattoo minors, and there don’t seem to be any issues with this. There isn’t any incentive for them to cause harm to their customers, on the contrary, so I don’t blame them for this. If tattooing poses serious health risks like this study suggests, it would suck for everyone involved.

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    • Øπ3ŕO Øπ3ŕ

      It’s good that you’ve expressed misconception as the source of this opinion, and admitted to your lack of understanding. The rest of the work could fall in nicely, if you put the effort forth. I’ll give ya one for free: “the culture around it” isn’t some singular entity, but a varied and colorful amalgam of countless inspirations, backgrounds, beliefs, reasons, etc., and the only thing that oversimplifying does here is stunt your personal growth.

      You got this. 🤘🏼

      T This user is from outside of this forum
      T This user is from outside of this forum
      Thymos
      wrote on last edited by
      #53

      Thanks, I’m good.

      Øπ3ŕO 1 Reply Last reply
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      • J jacksilver@lemmy.world

        And yet things like asbestos, lead, and smoking all took way longer than you’d expect (given they were a lot more universal).

        A This user is from outside of this forum
        A This user is from outside of this forum
        azertyfun@sh.itjust.works
        wrote on last edited by
        #54

        All three of your examples were known to cause ill effects for centuries. The ancient Romans knew the asbestos mines were killing their slaves. Their overuse during the 20th century was not due to ignorance but corporate lobbying and political complacency.

        The lobbyist play is to fund counter-studies to sow FUD even though the scientific consensus that [X Bad] is well established, because it gives an easy out for bought out politicians. However the tatoo lobby is certainly not one that I expect to be have the pull to fund FUD scientific studies to delay legislation, and if they are doing that it should be pretty easy to point to.

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        • underpantsweevil@lemmy.worldU underpantsweevil@lemmy.world

          It’s just tiresome to hear these hyperventilating articles without any real measure of the degree of risk or long term consequences.

          F This user is from outside of this forum
          F This user is from outside of this forum
          faythofdragons@slrpnk.net
          wrote on last edited by
          #55

          Honestly, I think that shitty science reporting like this is fuel for the normie to science skeptic pipeline.

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          • D dozensofdonner@mander.xyz

            Ah pretty interesting. Good to clarify that its in mice, not humans.

            A This user is from outside of this forum
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            aldente@sh.itjust.works
            wrote on last edited by
            #56

            Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

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            • KingK King

              Study

              The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

              The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

              B This user is from outside of this forum
              B This user is from outside of this forum
              bluesheep@sh.itjust.works
              wrote on last edited by
              #57

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              • KingK King

                Study

                The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                J This user is from outside of this forum
                J This user is from outside of this forum
                jhex@lemmy.world
                wrote on last edited by jhex@lemmy.world
                #58

                how low? weakened by how much?

                I think they leave that out on purpose so they can make these sensational claims… if your immune system takes a 0.02% hit, nobody would care

                P 1 Reply Last reply
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                • KingK King

                  Study

                  The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                  The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                  😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                  😈MedicPig🐷BabySaver😈M This user is from outside of this forum
                  😈MedicPig🐷BabySaver😈
                  wrote on last edited by
                  #59

                  Ha, get bent.

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                  • P03 LockeP P03 Locke

                    And yet, we manage to have hundreds of thousands of studies written about humans with human subjects. This sounds like a boatload of excuses that could be summed up as “science is hard”. Sure, it’s hard, but it’s better than putting out a flawed study that can’t scale properly.

                    bonenodeB This user is from outside of this forum
                    bonenodeB This user is from outside of this forum
                    bonenode
                    wrote on last edited by
                    #60

                    You don’t need to sum it up as science is hard but also as science is expensive. They might simply not have gotten funding for something as that.

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                    • KingK King

                      Study

                      The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                      The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                      A This user is from outside of this forum
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                      altphoto@lemmy.today
                      wrote on last edited by
                      #61

                      Link Preview Image
                      Tattoos - Mander

                      Lemmy

                      favicon

                      (mander.xyz)

                      S 1 Reply Last reply
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                      • KingK King

                        Study

                        The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                        The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                        arscynic@lemmy.mlA This user is from outside of this forum
                        arscynic@lemmy.mlA This user is from outside of this forum
                        arscynic@lemmy.ml
                        wrote on last edited by
                        #62

                        Steve-O is still alive; humanity will be fine.

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                        • stravanasuP stravanasu

                          Why not be a professional scientist by:

                          • adding “in mice” to the title;
                          • using modern statistical methods instead of continuously discredited procedures like p-values?
                          M This user is from outside of this forum
                          M This user is from outside of this forum
                          monkdervierte@lemmy.zip
                          wrote on last edited by
                          #63
                          • adding “in mice” to the title;

                          Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                          P03 LockeP 1 Reply Last reply
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                          • J jhex@lemmy.world

                            how low? weakened by how much?

                            I think they leave that out on purpose so they can make these sensational claims… if your immune system takes a 0.02% hit, nobody would care

                            P This user is from outside of this forum
                            P This user is from outside of this forum
                            Phoenixz
                            wrote on last edited by
                            #64

                            You’d care if it’s a 20% hit, though.

                            But you’re completely right, without any details, the claims are rather empty at best

                            J 1 Reply Last reply
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                            • KingK King

                              Study

                              The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                              The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                              gmtom@lemmy.worldG This user is from outside of this forum
                              gmtom@lemmy.worldG This user is from outside of this forum
                              gmtom@lemmy.world
                              wrote on last edited by
                              #65

                              Surely someone could check this by doing a statistical analysis of cancer patients with tattoos vs how many of the general population has tattoos?

                              B 1 Reply Last reply
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                              • G gusgalarnyk@lemmy.world

                                Why make this comment encouraging bad behavior? This feels like injected negativity for negativity sake. Idk man, be the change you want to see in your community.

                                S This user is from outside of this forum
                                S This user is from outside of this forum
                                sendmephotos@lemmy.world
                                wrote on last edited by
                                #66

                                Because I am a sarcastic fuck.

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                                • KingK King

                                  Study

                                  The researchers discovered that once a tattoo is made, the ink rapidly travels through the lymphatic system and, within hours, accumulates in large quantities in the lymph nodes — key organs of the body’s defense system. Inside these nodes, immune cells called macrophages actively capture all types of pigment. This ink uptake triggers an inflammatory response with two phases: an acute phase lasting about two days after tattooing, followed by a chronic phase that can persist for years. The chronic phase is particularly concerning because it weakens the immune system, potentially increasing the susceptibility to infections and cancer. The study also showed that macrophages cannot break down the ink like they would other pathogens, wich causes them to die, especially with red and black inks, suggesting these colors may be more toxic. As a result, ink remains trapped in the lymph nodes in a continuous cycle of capture and cell death, gradually affecting the immune system’s defensive capacity.

                                  The study found that tattooed mice produced significantly lower levels of antibodies after vaccination. This effect is likely due to the impaired function of immune cells that remain associated with tattoo ink for long periods. Similarly, human immune cells previously exposed to ink also showed a weakened response to vaccination.

                                  S This user is from outside of this forum
                                  S This user is from outside of this forum
                                  sinadjetivos@lemmy.world
                                  wrote on last edited by
                                  #67

                                  The full paper is here and, as usual, it’s hardly anything and decontextualized in order to get a publishable result.

                                  This one is so bad that it doesn’t use established baselines or do any form of statistical analysis on the results instead opting for their own “baseline” measurements using very small sample sizes. It also plays a smoke and mirrors game where it shows a result for short term immunological response and then uses that to insinuate the ‘slightly reduced but still likely well within the error of the poor control’ long term effects are worth noting.

                                  Other major flaws:

                                  • As others have mentioned, mice are a terrible model for this as their skin is very thin and proper tattooing is near impossible.
                                  • They mention verifying with human cadavers but don’t include any data from those.
                                  • There was no control group, the baseline was an untreated mouse, not one with an acute foot trauma.
                                  • Mice age very quickly, best I can tell the immunological markers weren’t age controlled. 2 months out of a <2 year lifespan is a lot of aging. Again, if there was a proper control to measure against.
                                  • The obsfucation of the raw data into cheesy and unreadable box and whisker plots is hella suspicious.

                                  At best it’s a very poorly communicated and poorly designed experiment but I suspect that’s due to it result hunting.

                                  P03 LockeP H 2 Replies Last reply
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                                  • H Horsey

                                    Human subjects are crazy to work with for a few reasons

                                    1. People don’t follow instructions perfectly
                                    2. Research subjects often don’t take the research project very seriously.
                                    3. It’s not uncommon to have dropouts, thus you either have to find more subjects or have less data.
                                    4. It’s impossible to know what the subjects are doing to cause data variability (diet, vices, etc)
                                    5. You can’t lock subjects in a room and force them to eat and drink the same food every day.
                                    6. There’s a financial (time) penalty to many research studies that can get in the way of enthusiastic participation.

                                    Laboratory mice literally live 5 to a cage with almost no diet variability, in a controlled environment. Yes shit does happen with research mice, but it’s something that is easy to control overall.

                                    _lilith@lemmy.world_ This user is from outside of this forum
                                    _lilith@lemmy.world_ This user is from outside of this forum
                                    _lilith@lemmy.world
                                    wrote on last edited by
                                    #68

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                                    • P Phoenixz

                                      You’d care if it’s a 20% hit, though.

                                      But you’re completely right, without any details, the claims are rather empty at best

                                      J This user is from outside of this forum
                                      J This user is from outside of this forum
                                      jhex@lemmy.world
                                      wrote on last edited by
                                      #69

                                      Absolutely! and having tattoos I care extra… the devil is always in the details

                                      In the society we live in, I’d guess the difference is minuscule so they hide the details to justify the headline

                                      Anecdotally, I live in Canada and tons of people have tattoos; health benchmarks are pretty decent here even if politicians have been trying really hard to dismatle our healthcare system… I feel we would have seen/suspected this before if it were significant (I work in healthcare)

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                                      • T Thymos

                                        Thanks, I’m good.

                                        Øπ3ŕO This user is from outside of this forum
                                        Øπ3ŕO This user is from outside of this forum
                                        Øπ3ŕ
                                        wrote on last edited by
                                        #70

                                        Hardly. 🤷🏼‍♂️ Not my monkey, not my circus. Good luck.

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                                        • S sendmephotos@lemmy.world

                                          … This is the internet. You can always be like the rest and pretend you know everything and are multi discaplined, instead of taking the proper, less fun, honest route.

                                          F This user is from outside of this forum
                                          F This user is from outside of this forum
                                          fartographer@lemmy.world
                                          wrote on last edited by
                                          #71

                                          As a triple MD of researchology and a minor in advanced bullshitterism, I can 100% confirm that the advice in this comment is the absolute healthiest way to interact with people on the Internet.

                                          Also, while the mice were only tested for two months after the tattoo, researchers continued to track the health of the mice via phone calls and getting together for after work beers every third Tuesday of the month.

                                          Source: I was probably one of the researchers or something.

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