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  3. The hidden mental health danger in today’s high-THC cannabis

The hidden mental health danger in today’s high-THC cannabis

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  • L lilililililil@lemmy.world

    So to be clear: because some unknown small sliver of the population may have an issue with it, you want to bubble wrap all of society?

    That sounds pretty conservative to me. Too much, even

    miskM This user is from outside of this forum
    miskM This user is from outside of this forum
    misk
    wrote on last edited by
    #25

    Where are you getting your numbers on % of population at risk of psychosis and schizophrenia to call them unknown small sliver? Cannabis being harmful to people under 25 is well studied. Most neurodivergent folk are at risk and both things compound enough so that having this kind of legal age just make sense.

    I consume plenty of weed myself but I’m for responsible and controlled use. I’m glad to piss off liberals and conservatives alike since I’m a leftie.

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    • W woodscientist@lemmy.world

      There is no age where the brain stops developing. The idea that the brain stops developing at age 25 is a myth. This myth comes brain studies that studied brain development…up to an age of 25. Pediatric studies of brain development don’t extend into far adulthood.

      Link Preview Image
      ‘Your brain isn’t fully formed until you’re 25’: A neuroscientist demolishes the greatest mind myth | BBC Science Focus Magazine

      Whether you are young or old, your brain is always changing.

      favicon

      BBC Science Focus Magazine (www.sciencefocus.com)

      miskM This user is from outside of this forum
      miskM This user is from outside of this forum
      misk
      wrote on last edited by
      #26

      Please stop using blog posts pretending to be scientific research.

      W 1 Reply Last reply
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      • miskM misk

        Please stop using blog posts pretending to be scientific research.

        W This user is from outside of this forum
        W This user is from outside of this forum
        woodscientist@lemmy.world
        wrote on last edited by
        #27

        Please stop posting comments offering nothing of value.

        miskM 1 Reply Last reply
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        • W woodscientist@lemmy.world

          Please stop posting comments offering nothing of value.

          miskM This user is from outside of this forum
          miskM This user is from outside of this forum
          misk
          wrote on last edited by
          #28

          I’d rather add meta-comment in an effort to preserve quality of discussion. I’m seeing this everywhere - making a point by linking to a blog pretending to be a scientific paper. It has about as much value as a comment by anyone here. If I understand correctly it’s an attempt to add some kind of authority to your opinion but it’s just harmful to the way establishing truth works.

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          • miskM misk

            I’d rather add meta-comment in an effort to preserve quality of discussion. I’m seeing this everywhere - making a point by linking to a blog pretending to be a scientific paper. It has about as much value as a comment by anyone here. If I understand correctly it’s an attempt to add some kind of authority to your opinion but it’s just harmful to the way establishing truth works.

            W This user is from outside of this forum
            W This user is from outside of this forum
            woodscientist@lemmy.world
            wrote on last edited by
            #29

            We’re talking on a casual forum. This isn’t an academic discussion. Blog posts are a lot more approachable than most journal articles. And blogs often contain references.

            Not everything is a formal academic debate. Most things aren’t. Note, you didn’t reply to the parent commenter demanding that they provide journal articles for their point. You just saw something you didn’t like about my comment and decided to demand a journal article as a citation. Usually when people who aren’t participating come into a discussion to demand peer-reviewed sources, it’s done in bad faith. They demand high quality sources from one side while not extending the same requirement to the other.

            Here’s another blog posts that address the original topic. You can look up the primary sources if you are so inclined.

            Link Preview Image
            So Your Brain Actually Isn’t “Fully Formed” at 25

            Your brain keeps developing beyond 25! Neuroplasticity in your late 20s to 30s makes you adaptable, resilient, and primed for growth.

            favicon

            New Hope CG (www.newhopecg.net)

            Or if you want to improve the quality of discussion, perhaps add your own sources instead of demanding others provide them.

            And note, even you don’t provide academic sources for your claims. You claim you’re seeing blog posts linked everywhere, but where is your journal article defending this claim? Where is your paper performing a statistical analysis to prove that people are citing blog posts more frequently than in the past?

            And I would argue that linking to a blog post is far from pointless. Blogs are less rigorous but far more approachable and digestible than journal articles. The real purpose of linking to them is so that a commenter doesn’t need to spend the time greatly elaborating a point that could be made simply by linking to a larger outside discussion. That has value. And a blog post certainly has more value than a random short Lemmy comment. At least if someone is taking the time to write a blog post dedicated to a single topic, it shows that they’ve put the time in to consider the subject.

            miskM 1 Reply Last reply
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            • P Pro
              This post did not contain any content.
              LustyArgonianL This user is from outside of this forum
              LustyArgonianL This user is from outside of this forum
              LustyArgonian
              wrote on last edited by lustyargonianmana@lemmy.world
              #30

              Willie Nelson looks great and sounds great for his age, with a case study like that I’m not putting down the cannabis

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              • F fenderstratocaster@lemmy.world

                THC is the least harmful, yet scariest drug I’ve ever taken.

                EDIT: I’m pretty sure you people are all high. I never said pot was dangerous. In fact, I said the opposite. I was making a point that high doses of THC are terrifying.

                LustyArgonianL This user is from outside of this forum
                LustyArgonianL This user is from outside of this forum
                LustyArgonian
                wrote on last edited by
                #31

                Try salvia

                F 1 Reply Last reply
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                • W woodscientist@lemmy.world

                  We’re talking on a casual forum. This isn’t an academic discussion. Blog posts are a lot more approachable than most journal articles. And blogs often contain references.

                  Not everything is a formal academic debate. Most things aren’t. Note, you didn’t reply to the parent commenter demanding that they provide journal articles for their point. You just saw something you didn’t like about my comment and decided to demand a journal article as a citation. Usually when people who aren’t participating come into a discussion to demand peer-reviewed sources, it’s done in bad faith. They demand high quality sources from one side while not extending the same requirement to the other.

                  Here’s another blog posts that address the original topic. You can look up the primary sources if you are so inclined.

                  Link Preview Image
                  So Your Brain Actually Isn’t “Fully Formed” at 25

                  Your brain keeps developing beyond 25! Neuroplasticity in your late 20s to 30s makes you adaptable, resilient, and primed for growth.

                  favicon

                  New Hope CG (www.newhopecg.net)

                  Or if you want to improve the quality of discussion, perhaps add your own sources instead of demanding others provide them.

                  And note, even you don’t provide academic sources for your claims. You claim you’re seeing blog posts linked everywhere, but where is your journal article defending this claim? Where is your paper performing a statistical analysis to prove that people are citing blog posts more frequently than in the past?

                  And I would argue that linking to a blog post is far from pointless. Blogs are less rigorous but far more approachable and digestible than journal articles. The real purpose of linking to them is so that a commenter doesn’t need to spend the time greatly elaborating a point that could be made simply by linking to a larger outside discussion. That has value. And a blog post certainly has more value than a random short Lemmy comment. At least if someone is taking the time to write a blog post dedicated to a single topic, it shows that they’ve put the time in to consider the subject.

                  miskM This user is from outside of this forum
                  miskM This user is from outside of this forum
                  misk
                  wrote on last edited by misk@piefed.social
                  #32

                  Truth isn’t different between serious and casual discussion and this is a serious topic.

                  If you want to cite a scientific paper then do it yourself and don’t ask others to fish them out of blogs you link to because too many times I’ve seen none included and nobody got time for that on a casual forum.

                  As to actual sources, I assumed I wouldn’t have to make as much of a strong point when talking about something that’s pretty much a scientific consensus. Where I live doctors won’t prescribe you medicinal weed if you’re under 25 usually too.

                  Going by casual wisdom, extraordinary claims require extraordinary evidence so I would expect the burden to be on the ones claiming that what I’m saying is bs but I guess it’s on me to bring back some reason here.

                  • Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review (closed access, SciDB mirror)
                  • Age-related differences in the impact of cannabis use on the brain and cognition: a systematic review
                  • Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents
                  • The Effect of Age of Initiation of Cannabis Use on Psychosis, Depression, and Anxiety among Youth under 25 Years
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                  • LustyArgonianL LustyArgonian

                    Try salvia

                    F This user is from outside of this forum
                    F This user is from outside of this forum
                    fenderstratocaster@lemmy.world
                    wrote on last edited by
                    #33

                    I did. That shit was wild. Didn’t get too much anxiety though. Weird shit started to happen.

                    C LustyArgonianL 2 Replies Last reply
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                    • M motoash@lemmy.world

                      “That is straight up stupid. Sugar is not a drug. …”

                      This you?

                      F This user is from outside of this forum
                      F This user is from outside of this forum
                      fenderstratocaster@lemmy.world
                      wrote on last edited by
                      #34

                      After 2 separate people started talking about sugar. I feel like I’m taking crazy pills

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                      • F fenderstratocaster@lemmy.world

                        I did. That shit was wild. Didn’t get too much anxiety though. Weird shit started to happen.

                        C This user is from outside of this forum
                        C This user is from outside of this forum
                        chakravanti@monero.town
                        wrote on last edited by chakravanti@monero.town
                        #35

                        Dissociatives phenomenally well translate all the weirdness of Salvia D. Especially DXM.

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                        • P Pro
                          This post did not contain any content.
                          Z This user is from outside of this forum
                          Z This user is from outside of this forum
                          zamboni_driver@lemmy.ca
                          wrote on last edited by
                          #36

                          This article brought to you by Budweiser

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                            This post did not contain any content.
                            V This user is from outside of this forum
                            V This user is from outside of this forum
                            vala@lemmy.dbzer0.com
                            wrote on last edited by vala@lemmy.dbzer0.com
                            #37

                            I get that this is fear mongering propaganda but also, I kinda hate that you can’t buy any old school pot anymore.

                            28% THC with no CBD just isn’t very enjoyable to me tbh.

                            I miss that stuff that was like 18% THC and at least 0.5% CBD.

                            H Øπ3ŕO B 3 Replies Last reply
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                            • V vala@lemmy.dbzer0.com

                              I get that this is fear mongering propaganda but also, I kinda hate that you can’t buy any old school pot anymore.

                              28% THC with no CBD just isn’t very enjoyable to me tbh.

                              I miss that stuff that was like 18% THC and at least 0.5% CBD.

                              H This user is from outside of this forum
                              H This user is from outside of this forum
                              honytawk@feddit.nl
                              wrote on last edited by
                              #38

                              You can also just buy straight up CBD and mix until your hearts content.

                              You don’t have to fill it to the brim with high grade pot if you don’t want to.

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                              • LustyArgonianL LustyArgonian

                                Willie Nelson looks great and sounds great for his age, with a case study like that I’m not putting down the cannabis

                                H This user is from outside of this forum
                                H This user is from outside of this forum
                                honytawk@feddit.nl
                                wrote on last edited by
                                #39

                                I mean, outliers always exist. Don’t think those are the norm.

                                LustyArgonianL 1 Reply Last reply
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                                • F fenderstratocaster@lemmy.world

                                  THC is the least harmful, yet scariest drug I’ve ever taken.

                                  EDIT: I’m pretty sure you people are all high. I never said pot was dangerous. In fact, I said the opposite. I was making a point that high doses of THC are terrifying.

                                  H This user is from outside of this forum
                                  H This user is from outside of this forum
                                  honytawk@feddit.nl
                                  wrote on last edited by
                                  #40

                                  You’re right, don’t mind the other commenters.

                                  With edibles or just strong weed, you can have heart palpitations that make you think you are dying. You aren’t actually going to, but it can feel that way when you are mega stoned.

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                                  • V vala@lemmy.dbzer0.com

                                    I get that this is fear mongering propaganda but also, I kinda hate that you can’t buy any old school pot anymore.

                                    28% THC with no CBD just isn’t very enjoyable to me tbh.

                                    I miss that stuff that was like 18% THC and at least 0.5% CBD.

                                    Øπ3ŕO This user is from outside of this forum
                                    Øπ3ŕO This user is from outside of this forum
                                    Øπ3ŕ
                                    wrote on last edited by otter@lemmy.dbzer0.com
                                    #41

                                    1.) It’s stupid easy to grow your own for next to nothing, in “stealth” containers ranging from 5gal buckets to full-on multi-plant gargants. (See: “space buckets” — and check your local laws)

                                    2.) It’s called weed for a reason. Set a reminder on your phone to water, prune, tend to your buddy. Spend as little or as much as you feel like, depending on how into the new, meditative hobby you’ve embarked on.

                                    3.) Realize you’ve been spending far too much on something you can set & (mostly) forget.

                                    4.) Enjoy!

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                                    • medgremlin@midwest.socialM medgremlin@midwest.social

                                      Schizophrenia is a mental health disorder that can be triggered by psychoactive substances, trauma, or other significant events/life changes. Not everyone who has schizophrenia was guaranteed to get it, it’s just that some people have the potential for it. A psychotic episode (whether substance-induced or organic) is a common trigger to cause schizophrenia in someone that had the potential to develop the disorder.

                                      If you have a family history of mental illnesses (particularly Schizophrenia and Bipolar disorder), significant THC use and substance-induced psychotic episodes can be the grain that tips the scale towards developing the disorder that may have otherwise been avoided.

                                      (TL;DR: if Schizophrenia runs in your family, be exceedingly careful about what psychoactive substances you use.)

                                      Øπ3ŕO This user is from outside of this forum
                                      Øπ3ŕO This user is from outside of this forum
                                      Øπ3ŕ
                                      wrote on last edited by
                                      #42

                                      Yep. I had a close friend that accepted a grip of shrooms from some random chicks at a house party, only to find out the hard way that night that his estranged (since ~birth) father’s side of the family had a high risk for schizophrenia… Be careful, friends. Knowledge is power. Use your damn brains, please.

                                      medgremlin@midwest.socialM 1 Reply Last reply
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                                      • Øπ3ŕO Øπ3ŕ

                                        Yep. I had a close friend that accepted a grip of shrooms from some random chicks at a house party, only to find out the hard way that night that his estranged (since ~birth) father’s side of the family had a high risk for schizophrenia… Be careful, friends. Knowledge is power. Use your damn brains, please.

                                        medgremlin@midwest.socialM This user is from outside of this forum
                                        medgremlin@midwest.socialM This user is from outside of this forum
                                        medgremlin@midwest.social
                                        wrote on last edited by
                                        #43

                                        I work in medicine (mostly emergency medicine), and I have seen a lot of people end up with their lives completely torn apart because of permanent effects of psychotropic drugs. CBD has a lot of benefits and some real clinical evidence backing it up, but there really aren’t any non-recreational uses for THC and the people who want to use marijuana for calming effects can get CBD on its own these days.

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                                        • A atomicbocks@sh.itjust.works

                                          Schizophrenia is better treated the earlier it is diagnosed. We are not talking about people who “might develop schizophrenia one day” but those who found out they had it as a result of this process perhaps earlier than they would have otherwise.

                                          medgremlin@midwest.socialM This user is from outside of this forum
                                          medgremlin@midwest.socialM This user is from outside of this forum
                                          medgremlin@midwest.social
                                          wrote on last edited by
                                          #44

                                          The earlier its diagnosed, the more severe it tends to be. If someone has schizophrenia triggered under the age of 25, the massive shift in the balance of neurotransmitters has a significant effect on the continuing development of the brain. The frontal cortex (the executive function, intelligence/wisdom, and common sense part of the brain) is the last part to finish developing. That’s why you can have teenagers and college-aged kids that are extremely smart academically, but absolute morons when it comes to decision making and self-restraint.

                                          Schizophrenia is characterized by massive overloading of dopamine to the point that the brain malfunctions, and the medications used to treat it (anti-psychotics) mostly work by dulling the effects of dopamine and limiting its production. Finding the right anti-psychotic and right dose of that drug can take a lot of trial and error, and that’s all time lost for ongoing development of that person’s brain. Dopamine is a very important neurotransmitter, so if someone has severe schizophrenia requiring strong dopamine inhibition, they can end up with a lot of nasty side effects.

                                          The medications have long term effects too and there’s kind of a maximum amount of time you can be on an anti-psychotic before you start having a form of medication-induced Parkinsonism. If someone’s schizophrenia gets triggered then diagnosed and treated earlier, it means they are going to start having those Parkinson’s symptoms that much earlier.

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