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Organs cannot simply be classified as male or female

Human organs form a mosaic of sex-specific characteristics

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Repetitive negative thinking is associated with cognitive function decline in older adults: a cross-sectional study - BMC Psychiatry

Psychological problems such as depression and anxiety increase the risk of cognitive impairment in older adults. But mechanisms on the effect of psychological disorder on cognitive function is inconclusive. Repetitive negative thinking (RNT) is a core symptom of a number of common psychological disorders and may be a modifiable process shared by many psychological risk factors that contribute to the development of cognitive impairment. RNT may increase the risk of cognitive impairment. However, there are fewer studies related to RNT and cognitive function, and there is a lack of epidemiological studies to explore the relationship between RNT and cognitive function. A cross-sectional study of 424 older adults aged 60 years or over was performed form May to November 2023 in hospital. To investigate the RNT level by using the Perseverative Thinking Questionnaire (PTQ), and investigate the cognitive function level by using the Montreal Cognitive Assessment Scale (MoCA). Multivariable linear regression and subgroup analyses were used to explore the relationship between RNT and cognitive function. We categorized the total RNT scores into quartiles. The multivariable linear regression analysis showed that after adjusting for all covariates, the participants in the Q3 and Q4 groups exhibited lower cognition scores (Q3:β = -0.180, 95%CI -2.849~-0.860; Q4:β = -0.164, 95% -2.611~-0.666) compared to the Q1 group. The results of the subgroup analyses showed that individuals aged 60 ~ 79 years, junior high school and above are more prone to suffer from cognitive impairment with a high RNT score. The study reveals a negative association between RNT and cognitive function in community-dwelling older adults. However, multi-center and a longer time span cohort studies on the relationship between RNT and cognitive function should be carried out to further explore the mechanisms involved.

Physicists have created a new 'time crystal'—it won't power a time machine but could have many other uses

A team at CU Boulder has made a curious state of matter in which particles move constantly—like a clock with hands and gears that spin forever, even without electricity to keep them going.

Emory report shows connection between mental health and heart disease, increased mortality risks | Emory University | Atlanta GA

A new study from Emory University shows that certain mental health conditions escalate the risk of developing heart disease and experiencing adverse outcomes by significant margins. The study also examines social determinants and quality of care.

Happy music could help you recover from motion sickness

Listening to joyful music helped study participants with motion sickness recover better than other participants — while sad music helped less than doing nothing

New AI tool identifies 1,000 'questionable' scientific journals

Questionable scientific journals, or those that publish studies without proper vetting for a profit, are growing around the world. A new AI system automatically seeks them out.

Neurobiological substrates of altered states of consciousness induced by high ventilation breathwork accompanied by music

The popularity of breathwork as a therapeutic tool for psychological distress is rapidly expanding. Breathwork practices that increase ventilatory rate or depth, facilitated by music, can evoke subjective experiential states analogous to altered states of consciousness (ASCs) evoked by psychedelic substances. These states include components such as euphoria, bliss, and perceptual differences. However, the neurobiological mechanisms underlying the profound subjective effects of high ventilation breathwork (HVB) remain largely unknown and unexplored. In this study, we investigated the neurobiological substrates of ASCs induced by HVB in experienced practitioners. We demonstrate that the intensity of ASCs evoked by HVB was proportional to cardiovascular sympathetic activation and to haemodynamic alterations in cerebral perfusion within clusters spanning the left operculum/posterior insula and right amygdala/anterior hippocampus; regions implicated in respiratory interoceptive representation and the processing of emotional memories, respectively. These observed regional cerebral effects may underlie pivotal mental experiences that mediate positive therapeutic outcomes of HVB.

‘Built for cutting flesh, not resisting acidity’: sharks may be losing deadly teeth to ocean acidification

Scientists found that some of the oceans’ fiercest hunters could be losing their bite: As oceans become more acidic, sharks’ teeth may become structurally weake