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  3. Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

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  • fossilesque@mander.xyzF fossilesque@mander.xyz
    This post did not contain any content.
    Riddick3001H This user is from outside of this forum
    Riddick3001H This user is from outside of this forum
    Riddick3001
    wrote on last edited by
    #3

    We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

    N 1 Reply Last reply
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    • fossilesque@mander.xyzF fossilesque@mander.xyz
      This post did not contain any content.
      jeffw@lemmy.worldJ This user is from outside of this forum
      jeffw@lemmy.worldJ This user is from outside of this forum
      jeffw@lemmy.world
      wrote on last edited by
      #4

      Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

      remotelove@lemmy.caR 1 Reply Last reply
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      • Riddick3001H Riddick3001

        We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

        N This user is from outside of this forum
        N This user is from outside of this forum
        NaibofTabr
        wrote on last edited by
        #5

        Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

        M Øπ3ŕO L steal_your_face@lemmy.mlS vanilla_puddinfudge@infosec.pubV 6 Replies Last reply
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        • fossilesque@mander.xyzF fossilesque@mander.xyz
          This post did not contain any content.
          OgmiosO This user is from outside of this forum
          OgmiosO This user is from outside of this forum
          Ogmios
          wrote on last edited by
          #6

          Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

          BurgerBaronB 1 Reply Last reply
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          • OgmiosO Ogmios

            Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

            BurgerBaronB This user is from outside of this forum
            BurgerBaronB This user is from outside of this forum
            BurgerBaron
            wrote on last edited by
            #7

            You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

            OgmiosO 1 Reply Last reply
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            • N NaibofTabr

              Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

              M This user is from outside of this forum
              M This user is from outside of this forum
              mac@mander.xyz
              wrote on last edited by mac@mander.xyz
              #8

              edit: double post

              1 Reply Last reply
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              • N NaibofTabr

                Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                M This user is from outside of this forum
                M This user is from outside of this forum
                mac@mander.xyz
                wrote on last edited by
                #9

                🤷‍♂️

                Okay, sure, why not

                1 Reply Last reply
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                • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

                  Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

                  So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That’s also like almost half an ounce of dried mushrooms. Time to start tripping… for science.

                  H This user is from outside of this forum
                  H This user is from outside of this forum
                  hootinnhollerin@lemmy.dbzer0.com
                  wrote on last edited by
                  #10

                  1 oz is 28.35 g

                  BodyBySisyphus [he/him]B 1 Reply Last reply
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                  • H hootinnhollerin@lemmy.dbzer0.com

                    1 oz is 28.35 g

                    BodyBySisyphus [he/him]B This user is from outside of this forum
                    BodyBySisyphus [he/him]B This user is from outside of this forum
                    BodyBySisyphus [he/him]
                    wrote on last edited by
                    #11

                    Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

                    C 1 Reply Last reply
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                    • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

                      Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

                      C This user is from outside of this forum
                      C This user is from outside of this forum
                      Castor_Troy [comrade/them,he/him]
                      wrote on last edited by castor_troy@hexbear.net
                      #12

                      (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                      1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

                      I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

                      M 1 Reply Last reply
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                      • C Castor_Troy [comrade/them,he/him]

                        (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                        1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

                        I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

                        M This user is from outside of this forum
                        M This user is from outside of this forum
                        Maturin [any]
                        wrote on last edited by
                        #13

                        Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                        C 2 Replies Last reply
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                        • fossilesque@mander.xyzF fossilesque@mander.xyz
                          This post did not contain any content.
                          W This user is from outside of this forum
                          W This user is from outside of this forum
                          wideopenarms [he/him]
                          wrote on last edited by wideopenarms@hexbear.net
                          #14

                          Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                          Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                          Øπ3ŕO isolatedscotch@discuss.tchncs.deI 2 Replies Last reply
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                          • jeffw@lemmy.worldJ jeffw@lemmy.world

                            Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

                            remotelove@lemmy.caR This user is from outside of this forum
                            remotelove@lemmy.caR This user is from outside of this forum
                            remotelove@lemmy.ca
                            wrote on last edited by
                            #15

                            Oh, I am going to try to replicate this study. I’ll hit you back in about 50 years if it worked.

                            jeffw@lemmy.worldJ 1 Reply Last reply
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                            • W wideopenarms [he/him]

                              Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                              Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                              Øπ3ŕO This user is from outside of this forum
                              Øπ3ŕO This user is from outside of this forum
                              Øπ3ŕ
                              wrote on last edited by
                              #16

                              You do you. Have fun!

                              1 Reply Last reply
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                              • N NaibofTabr

                                Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                                Øπ3ŕO This user is from outside of this forum
                                Øπ3ŕO This user is from outside of this forum
                                Øπ3ŕ
                                wrote on last edited by
                                #17

                                Did you drop this? /s

                                You’re making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

                                1 Reply Last reply
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                                • BurgerBaronB BurgerBaron

                                  You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

                                  OgmiosO This user is from outside of this forum
                                  OgmiosO This user is from outside of this forum
                                  Ogmios
                                  wrote on last edited by
                                  #18

                                  Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                                  BurgerBaronB 1 Reply Last reply
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                                  • fossilesque@mander.xyzF fossilesque@mander.xyz
                                    This post did not contain any content.
                                    L This user is from outside of this forum
                                    L This user is from outside of this forum
                                    laser@feddit.org
                                    wrote on last edited by
                                    #19

                                    A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

                                    Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a “byproduct” is kind of underselling it. Psilocybin itself isn’t active by itself.

                                    Quick wiki check confirms this. I always have troubles with articles opening with. I can’t even read that as unfortunate wording.

                                    1 Reply Last reply
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                                    • OgmiosO Ogmios

                                      Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                                      BurgerBaronB This user is from outside of this forum
                                      BurgerBaronB This user is from outside of this forum
                                      BurgerBaron
                                      wrote on last edited by
                                      #20

                                      Your sarcasm is noted, but seems daft when you suggest you’ll live longer because you ate a funny mushroom a couple times.

                                      OgmiosO 1 Reply Last reply
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                                      • N NaibofTabr

                                        Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                                        L This user is from outside of this forum
                                        L This user is from outside of this forum
                                        lb_o@lemmy.world
                                        wrote on last edited by
                                        #21

                                        WE ARE THE ONE!

                                        1 Reply Last reply
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                                        • fossilesque@mander.xyzF fossilesque@mander.xyz
                                          This post did not contain any content.
                                          B This user is from outside of this forum
                                          B This user is from outside of this forum
                                          bronzebeard@lemmy.zip
                                          wrote on last edited by
                                          #22

                                          Nuh uh. I’ve seen the Last of US. We all know where this ends up

                                          1 Reply Last reply
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