Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That’s also like almost half an ounce of dried mushrooms. Time to start tripping… for science.

We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

edit: double post

‍️

Okay, sure, why not

1 oz is 28.35 g

Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

(15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

Go ahead and hit me with the , don’t care if that’s an L take or not

Oh, I am going to try to replicate this study. I’ll hit you back in about 50 years if it worked.

You do you. Have fun!

Did you drop this? /s

You’re making it sound pretty damn amazing, frankly. Have you looked around lately? ‍️

Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a “byproduct” is kind of underselling it. Psilocybin itself isn’t active by itself.

Quick wiki check confirms this. I always have troubles with articles opening with. I can’t even read that as unfortunate wording.

Your sarcasm is noted, but seems daft when you suggest you’ll live longer because you ate a funny mushroom a couple times.