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  3. Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

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  • OgmiosO Ogmios

    Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

    BurgerBaronB This user is from outside of this forum
    BurgerBaronB This user is from outside of this forum
    BurgerBaron
    wrote on last edited by
    #7

    You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

    OgmiosO 1 Reply Last reply
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    • N NaibofTabr

      Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

      M This user is from outside of this forum
      M This user is from outside of this forum
      mac@mander.xyz
      wrote on last edited by mac@mander.xyz
      #8

      edit: double post

      1 Reply Last reply
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      • N NaibofTabr

        Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

        M This user is from outside of this forum
        M This user is from outside of this forum
        mac@mander.xyz
        wrote on last edited by
        #9

        🤷‍♂️

        Okay, sure, why not

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        • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

          Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

          So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That’s also like almost half an ounce of dried mushrooms. Time to start tripping… for science.

          H This user is from outside of this forum
          H This user is from outside of this forum
          hootinnhollerin@lemmy.dbzer0.com
          wrote on last edited by
          #10

          1 oz is 28.35 g

          BodyBySisyphus [he/him]B 1 Reply Last reply
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          • H hootinnhollerin@lemmy.dbzer0.com

            1 oz is 28.35 g

            BodyBySisyphus [he/him]B This user is from outside of this forum
            BodyBySisyphus [he/him]B This user is from outside of this forum
            BodyBySisyphus [he/him]
            wrote on last edited by
            #11

            Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

            C 1 Reply Last reply
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            • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

              Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

              C This user is from outside of this forum
              C This user is from outside of this forum
              Castor_Troy [comrade/them,he/him]
              wrote on last edited by castor_troy@hexbear.net
              #12

              (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

              1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

              I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

              M 1 Reply Last reply
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              • C Castor_Troy [comrade/them,he/him]

                (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

                I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

                M This user is from outside of this forum
                M This user is from outside of this forum
                Maturin [any]
                wrote on last edited by
                #13

                Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                C 2 Replies Last reply
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                • fossilesque@mander.xyzF fossilesque@mander.xyz
                  This post did not contain any content.
                  W This user is from outside of this forum
                  W This user is from outside of this forum
                  wideopenarms [he/him]
                  wrote on last edited by wideopenarms@hexbear.net
                  #14

                  Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                  Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                  Øπ3ŕO isolatedscotch@discuss.tchncs.deI 2 Replies Last reply
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                  • jeffw@lemmy.worldJ jeffw@lemmy.world

                    Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

                    remotelove@lemmy.caR This user is from outside of this forum
                    remotelove@lemmy.caR This user is from outside of this forum
                    remotelove@lemmy.ca
                    wrote on last edited by
                    #15

                    Oh, I am going to try to replicate this study. I’ll hit you back in about 50 years if it worked.

                    jeffw@lemmy.worldJ 1 Reply Last reply
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                    • W wideopenarms [he/him]

                      Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                      Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                      Øπ3ŕO This user is from outside of this forum
                      Øπ3ŕO This user is from outside of this forum
                      Øπ3ŕ
                      wrote on last edited by
                      #16

                      You do you. Have fun!

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                      • N NaibofTabr

                        Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                        Øπ3ŕO This user is from outside of this forum
                        Øπ3ŕO This user is from outside of this forum
                        Øπ3ŕ
                        wrote on last edited by
                        #17

                        Did you drop this? /s

                        You’re making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

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                        • BurgerBaronB BurgerBaron

                          You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

                          OgmiosO This user is from outside of this forum
                          OgmiosO This user is from outside of this forum
                          Ogmios
                          wrote on last edited by
                          #18

                          Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                          BurgerBaronB 1 Reply Last reply
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                          • fossilesque@mander.xyzF fossilesque@mander.xyz
                            This post did not contain any content.
                            L This user is from outside of this forum
                            L This user is from outside of this forum
                            laser@feddit.org
                            wrote on last edited by
                            #19

                            A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

                            Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a “byproduct” is kind of underselling it. Psilocybin itself isn’t active by itself.

                            Quick wiki check confirms this. I always have troubles with articles opening with. I can’t even read that as unfortunate wording.

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                            • OgmiosO Ogmios

                              Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                              BurgerBaronB This user is from outside of this forum
                              BurgerBaronB This user is from outside of this forum
                              BurgerBaron
                              wrote on last edited by
                              #20

                              Your sarcasm is noted, but seems daft when you suggest you’ll live longer because you ate a funny mushroom a couple times.

                              OgmiosO 1 Reply Last reply
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                              • N NaibofTabr

                                Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                                L This user is from outside of this forum
                                L This user is from outside of this forum
                                lb_o@lemmy.world
                                wrote on last edited by
                                #21

                                WE ARE THE ONE!

                                1 Reply Last reply
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                                • fossilesque@mander.xyzF fossilesque@mander.xyz
                                  This post did not contain any content.
                                  B This user is from outside of this forum
                                  B This user is from outside of this forum
                                  bronzebeard@lemmy.zip
                                  wrote on last edited by
                                  #22

                                  Nuh uh. I’ve seen the Last of US. We all know where this ends up

                                  1 Reply Last reply
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                                  • W wideopenarms [he/him]

                                    Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                                    Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                                    isolatedscotch@discuss.tchncs.deI This user is from outside of this forum
                                    isolatedscotch@discuss.tchncs.deI This user is from outside of this forum
                                    isolatedscotch@discuss.tchncs.de
                                    wrote on last edited by
                                    #23

                                    no healthy adult should feel the need to take any drug

                                    rivalarrival@lemmy.todayR 1 Reply Last reply
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                                    • M Maturin [any]

                                      Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                                      C This user is from outside of this forum
                                      C This user is from outside of this forum
                                      Castor_Troy [comrade/them,he/him]
                                      wrote on last edited by
                                      #24

                                      Thank you. I was staring at it and knew the units weren’t canceling out. That’s an insane dose though.

                                      M 1 Reply Last reply
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                                      • M Maturin [any]

                                        Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                                        C This user is from outside of this forum
                                        C This user is from outside of this forum
                                        Castor_Troy [comrade/them,he/him]
                                        wrote on last edited by
                                        #25

                                        (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                                        1200 mg psilocybin = 1.2 g psilocybin * (100 g dried mushrooms / 1 g psilocybin) = 120 g dried mushrooms

                                        There we go.

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                                        • C Castor_Troy [comrade/them,he/him]

                                          Thank you. I was staring at it and knew the units weren’t canceling out. That’s an insane dose though.

                                          M This user is from outside of this forum
                                          M This user is from outside of this forum
                                          Maturin [any]
                                          wrote on last edited by
                                          #26

                                          Even the “low dose” is the equivalent of almost 2 oz per dose. Those mice got to convene with the mice gods on the reg I’m sure.

                                          propter_hog [any, any]P 1 Reply Last reply
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