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  3. Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

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  • fossilesque@mander.xyzF fossilesque@mander.xyz
    This post did not contain any content.
    OgmiosO This user is from outside of this forum
    OgmiosO This user is from outside of this forum
    Ogmios
    wrote on last edited by
    #6

    Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

    BurgerBaronB 1 Reply Last reply
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    • OgmiosO Ogmios

      Well, I know I’ve done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn’t showing the ordinary signs of aging. Wonder if it’s related.

      BurgerBaronB This user is from outside of this forum
      BurgerBaronB This user is from outside of this forum
      BurgerBaron
      wrote on last edited by
      #7

      You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

      OgmiosO 1 Reply Last reply
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      • N NaibofTabr

        Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

        M This user is from outside of this forum
        M This user is from outside of this forum
        mac@mander.xyz
        wrote on last edited by mac@mander.xyz
        #8

        edit: double post

        1 Reply Last reply
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        • N NaibofTabr

          Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

          M This user is from outside of this forum
          M This user is from outside of this forum
          mac@mander.xyz
          wrote on last edited by
          #9

          🤷‍♂️

          Okay, sure, why not

          1 Reply Last reply
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          • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

            Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

            So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That’s also like almost half an ounce of dried mushrooms. Time to start tripping… for science.

            H This user is from outside of this forum
            H This user is from outside of this forum
            hootinnhollerin@lemmy.dbzer0.com
            wrote on last edited by
            #10

            1 oz is 28.35 g

            BodyBySisyphus [he/him]B 1 Reply Last reply
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            • H hootinnhollerin@lemmy.dbzer0.com

              1 oz is 28.35 g

              BodyBySisyphus [he/him]B This user is from outside of this forum
              BodyBySisyphus [he/him]B This user is from outside of this forum
              BodyBySisyphus [he/him]
              wrote on last edited by
              #11

              Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

              C 1 Reply Last reply
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              • BodyBySisyphus [he/him]B BodyBySisyphus [he/him]

                Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

                C This user is from outside of this forum
                C This user is from outside of this forum
                Castor_Troy [comrade/them,he/him]
                wrote on last edited by castor_troy@hexbear.net
                #12

                (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

                I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

                M 1 Reply Last reply
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                • C Castor_Troy [comrade/them,he/him]

                  (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                  1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

                  I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

                  M This user is from outside of this forum
                  M This user is from outside of this forum
                  Maturin [any]
                  wrote on last edited by
                  #13

                  Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                  C 2 Replies Last reply
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                  • fossilesque@mander.xyzF fossilesque@mander.xyz
                    This post did not contain any content.
                    W This user is from outside of this forum
                    W This user is from outside of this forum
                    wideopenarms [he/him]
                    wrote on last edited by wideopenarms@hexbear.net
                    #14

                    Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                    Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                    Øπ3ŕO isolatedscotch@discuss.tchncs.deI 2 Replies Last reply
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                    • jeffw@lemmy.worldJ jeffw@lemmy.world

                      Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

                      remotelove@lemmy.caR This user is from outside of this forum
                      remotelove@lemmy.caR This user is from outside of this forum
                      remotelove@lemmy.ca
                      wrote on last edited by
                      #15

                      Oh, I am going to try to replicate this study. I’ll hit you back in about 50 years if it worked.

                      jeffw@lemmy.worldJ 1 Reply Last reply
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                      • W wideopenarms [he/him]

                        Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                        Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                        Øπ3ŕO This user is from outside of this forum
                        Øπ3ŕO This user is from outside of this forum
                        Øπ3ŕ
                        wrote on last edited by
                        #16

                        You do you. Have fun!

                        1 Reply Last reply
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                        • N NaibofTabr

                          Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                          Øπ3ŕO This user is from outside of this forum
                          Øπ3ŕO This user is from outside of this forum
                          Øπ3ŕ
                          wrote on last edited by
                          #17

                          Did you drop this? /s

                          You’re making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

                          1 Reply Last reply
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                          • BurgerBaronB BurgerBaron

                            You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

                            OgmiosO This user is from outside of this forum
                            OgmiosO This user is from outside of this forum
                            Ogmios
                            wrote on last edited by
                            #18

                            Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                            BurgerBaronB 1 Reply Last reply
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                            • fossilesque@mander.xyzF fossilesque@mander.xyz
                              This post did not contain any content.
                              L This user is from outside of this forum
                              L This user is from outside of this forum
                              laser@feddit.org
                              wrote on last edited by
                              #19

                              A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

                              Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a “byproduct” is kind of underselling it. Psilocybin itself isn’t active by itself.

                              Quick wiki check confirms this. I always have troubles with articles opening with. I can’t even read that as unfortunate wording.

                              1 Reply Last reply
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                              • OgmiosO Ogmios

                                Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

                                BurgerBaronB This user is from outside of this forum
                                BurgerBaronB This user is from outside of this forum
                                BurgerBaron
                                wrote on last edited by
                                #20

                                Your sarcasm is noted, but seems daft when you suggest you’ll live longer because you ate a funny mushroom a couple times.

                                OgmiosO 1 Reply Last reply
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                                • N NaibofTabr

                                  Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

                                  L This user is from outside of this forum
                                  L This user is from outside of this forum
                                  lb_o@lemmy.world
                                  wrote on last edited by
                                  #21

                                  WE ARE THE ONE!

                                  1 Reply Last reply
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                                  • fossilesque@mander.xyzF fossilesque@mander.xyz
                                    This post did not contain any content.
                                    B This user is from outside of this forum
                                    B This user is from outside of this forum
                                    bronzebeard@lemmy.zip
                                    wrote on last edited by
                                    #22

                                    Nuh uh. I’ve seen the Last of US. We all know where this ends up

                                    1 Reply Last reply
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                                    • W wideopenarms [he/him]

                                      Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

                                      Go ahead and hit me with the downbear, don’t care if that’s an L take or not

                                      isolatedscotch@discuss.tchncs.deI This user is from outside of this forum
                                      isolatedscotch@discuss.tchncs.deI This user is from outside of this forum
                                      isolatedscotch@discuss.tchncs.de
                                      wrote on last edited by
                                      #23

                                      no healthy adult should feel the need to take any drug

                                      rivalarrival@lemmy.todayR 1 Reply Last reply
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                                      • M Maturin [any]

                                        Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                                        C This user is from outside of this forum
                                        C This user is from outside of this forum
                                        Castor_Troy [comrade/them,he/him]
                                        wrote on last edited by
                                        #24

                                        Thank you. I was staring at it and knew the units weren’t canceling out. That’s an insane dose though.

                                        M 1 Reply Last reply
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                                        • M Maturin [any]

                                          Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

                                          C This user is from outside of this forum
                                          C This user is from outside of this forum
                                          Castor_Troy [comrade/them,he/him]
                                          wrote on last edited by
                                          #25

                                          (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

                                          1200 mg psilocybin = 1.2 g psilocybin * (100 g dried mushrooms / 1 g psilocybin) = 120 g dried mushrooms

                                          There we go.

                                          1 Reply Last reply
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